| cGAS produces a 2'-5 '-linked cyclic dinucleotide second messenger that activates STING A Ablasser, M Goldeck, T Cavlar, T Deimling, G Witte, I Röhl, KP Hopfner, ... Nature, 2013 | 1466 | 2013 |
| Structural mechanism of cytosolic DNA sensing by cGAS F Civril, T Deimling, CC de Oliveira Mann, A Ablasser, M Moldt, G Witte, ... Nature 498 (7454), 332-337, 2013 | 755 | 2013 |
| Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates G Witte, S Hartung, K Büttner, KP Hopfner Molecular cell 30 (2), 167-178, 2008 | 493 | 2008 |
| Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes T Thestrup, J Litzlbauer, I Bartholomäus, M Mues, L Russo, H Dana, ... Nature Methods, 2014 | 387 | 2014 |
| cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells J Paijo, M Doring, J Spanier, E Grabski, M Nooruzzaman, T Schmidt, ... PLoS Pathogens 12 (4), e1005546, 2016 | 191 | 2016 |
| Structural basis for sequestration and autoinhibition of cGAS by chromatin S Michalski, CC de Oliveira Mann, C Stafford, G Witte, J Bartho, ... Nature, 2020 | 181 | 2020 |
| Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling C Motz, KM Schuhmann, A Kirchhofer, M Moldt, G Witte, KK Conzelmann, ... Science 339 (6120), 690-693, 2013 | 137 | 2013 |
| DNA polymerase III χ subunit ties single‐stranded DNA binding protein to the bacterial replication machinery G Witte, C Urbanke, U Curth Nucleic acids research 31 (15), 4434-4440, 2003 | 135 | 2003 |
| The RIG‐I ATPase domain structure reveals insights into ATP‐dependent antiviral signalling F Civril, M Bennett, M Moldt, T Deimling, G Witte, S Schiesser, T Carell, ... EMBO reports 12 (11), 1127-1134, 2011 | 117 | 2011 |
| Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth C Blattner, S Jennebach, F Herzog, A Mayer, ACM Cheung, G Witte, ... Genes & development 25 (19), 2093-2105, 2011 | 116 | 2011 |
| The phenotypic spectrum of neutral lipid storage myopathy due to mutations in the PNPLA2 gene P Reilich, R Horvath, S Krause, N Schramm, DM Turnbull, M Trenell, ... Journal of neurology 258, 1987-1997, 2011 | 115 | 2011 |
| Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins JJ Griese, G Witte, KP Hopfner Nucleic acids research 38 (10), 3454-3465, 2010 | 102 | 2010 |
| Structural characterization of a eukaryotic chaperone—the ribosome-associated complex C Leidig, G Bange, J Kopp, S Amlacher, A Aravind, S Wickles, G Witte, ... Nature structural & molecular biology 20 (1), 23-28, 2013 | 89 | 2013 |
| Structural biochemistry of nuclear actin‐related proteins 4 and 8 reveals their interaction with actin S Fenn, D Breitsprecher, CB Gerhold, G Witte, J Faix, KP Hopfner The EMBO journal 30 (11), 2153-2166, 2011 | 84 | 2011 |
| Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP P Wollmann, S Cui, R Viswanathan, O Berninghausen, MN Wells, M Moldt, ... Nature 475 (7356), 403-407, 2011 | 78 | 2011 |
| Structure of Actin-related protein 8 and its contribution to nucleosome binding CB Gerhold, DD Winkler, K Lakomek, FU Seifert, S Fenn, B Kessler, ... Nucleic acids research 40 (21), 11036-11046, 2012 | 64 | 2012 |
| Single-stranded DNA-binding protein of Deinococcus radiodurans: a biophysical characterization G Witte, C Urbanke, U Curth Nucleic acids research 33 (5), 1662-1670, 2005 | 63 | 2005 |
| c-di-AMP recognition by Staphylococcus aureus PstA M Müller, KP Hopfner, G Witte FEBS letters 589 (1), 45-51, 2014 | 60 | 2014 |
| Structural model for covalent adhesion of the Streptococcus pyogenes pilus through a thioester bond C Linke-Winnebeck, NG Paterson, PG Young, MJ Middleditch, ... Journal of Biological Chemistry 289 (1), 177-189, 2014 | 57 | 2014 |
| Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein R Banerjee, C Gladkova, K Mapa, G Witte, D Mokranjac eLife, 2015 | 54 | 2015 |
Christian Linke-WinnebeckAG Hopfner, Genzentrum, LMU University of MunichBestätigte E-Mail-Adresse bei genzentrum.lmu.de
