| Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine B van Loon, E Markkanen, U Hübscher DNA repair 9 (6), 604-616, 2010 | 366 | 2010 |
| Inhibiting WEE1 selectively kills histone H3K36me3-deficient cancers by dNTP starvation SX Pfister, E Markkanen, Y Jiang, S Sarkar, M Woodcock, G Orlando, ... Cancer cell 28 (5), 557-568, 2015 | 295 | 2015 |
| Targeting BRCA1 and BRCA2 deficiencies with G-quadruplex-interacting compounds J Zimmer, EMC Tacconi, C Folio, S Badie, M Porru, K Klare, M Tumiati, ... Molecular cell 61 (3), 449-460, 2016 | 230 | 2016 |
| Not breathing is not an option: How to deal with oxidative DNA damage E Markkanen DNA repair 59, 82-105, 2017 | 171 | 2017 |
| DNA damage and repair in schizophrenia and autism: implications for cancer comorbidity and beyond E Markkanen, U Meyer, GL Dianov International journal of molecular sciences 17 (6), 856, 2016 | 88 | 2016 |
| MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA E Markkanen, J Dorn, U Hübscher Frontiers in genetics 4, 44292, 2013 | 86 | 2013 |
| Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination E Markkanen, B van Loon, E Ferrari, JL Parsons, GL Dianov, U Hübscher Proceedings of the National Academy of Sciences 109 (2), 437-442, 2012 | 86 | 2012 |
| The human checkpoint sensor and alternative DNA clamp Rad9–Rad1–Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery E Smirnova, M Toueille, E Markkanen, U Hübscher Biochemical Journal 389 (Pt 1), 13, 2005 | 86 | 2005 |
| An optimised protocol for isolation of RNA from small sections of laser-capture microdissected FFPE tissue amenable for next-generation sequencing P Amini, J Ettlin, L Opitz, E Clementi, A Malbon, E Markkanen BMC Molecular biology 18, 1-11, 2017 | 59 | 2017 |
| DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7, 8-dihydroguanine bypass G Maga, E Crespan, E Markkanen, R Imhof, A Furrer, G Villani, ... Proceedings of the National Academy of Sciences 110 (47), 18850-18855, 2013 | 56 | 2013 |
| Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability E Markkanen, R Fischer, M Ledentcova, BM Kessler, GL Dianov Nucleic Acids Research 43 (7), 3667-3679, 2015 | 52 | 2015 |
| A switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesions E Markkanen, B Castrec, G Villani, U Hübscher Proceedings of the National Academy of Sciences 109 (50), 20401-20406, 2012 | 49 | 2012 |
| Regulation of oxidative DNA damage repair: the adenine: 8-oxo-guanine problem E Markkanen, U Hübscher, B van Loon Cell Cycle 11 (6), 1070-1075, 2012 | 48 | 2012 |
| Analysis of gene expression signatures in cancer-associated stroma from canine mammary tumours reveals molecular homology to human breast carcinomas J Ettlin, E Clementi, P Amini, A Malbon, E Markkanen International journal of molecular sciences 18 (5), 1101, 2017 | 43 | 2017 |
| Base excision repair in physiology and pathology of the central nervous system M Bosshard, E Markkanen, B Van Loon International journal of molecular sciences 13 (12), 16172-16222, 2012 | 40 | 2012 |
| In Vitro Gap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases ϵ, λ, and β G Villani, U Hubscher, N Gironis, S Parkkinen, H Pospiech, I Shevelev, ... Journal of Biological Chemistry 286 (37), 32094-32104, 2011 | 37 | 2011 |
| Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction E Clementi, L Inglin, E Beebe, C Gsell, Z Garajova, E Markkanen BMC biology 18, 1-15, 2020 | 33 | 2020 |
| Differential stromal reprogramming in benign and malignant naturally occurring canine mammary tumours identifies disease-modulating stromal components P Amini, S Nassiri, A Malbon, E Markkanen Scientific reports 10 (1), 5506, 2020 | 32 | 2020 |
| Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability M Bosshard, R Aprigliano, C Gattiker, V Palibrk, E Markkanen, PH Backe, ... Scientific reports 7 (1), 15050, 2017 | 31 | 2017 |
| Next-generation RNA sequencing of FFPE subsections reveals highly conserved stromal reprogramming between canine and human mammary carcinoma P Amini, S Nassiri, J Ettlin, A Malbon, E Markkanen Disease models & mechanisms 12 (8), dmm040444, 2019 | 26 | 2019 |
