Dorit Donoviel
Dorit Donoviel
Associate Professor, Space Medicine
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Cited by
Cited by
Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells
S Hitoshi, T Alexson, V Tropepe, D Donoviel, AJ Elia, JS Nye, RA Conlon, ...
Genes & development 16 (7), 846-858, 2002
Mice lacking both presenilin genes exhibitearlyembryonic patterningdefects
DB Donoviel, AK Hadjantonakis, M Ikeda, H Zheng, PSG Hyslop, ...
Genes & development 13 (21), 2801-2810, 1999
Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
DB Donoviel, DD Freed, H Vogel, DG Potter, E Hawkins, JP Barrish, ...
Molecular and cellular biology 21 (14), 4829-4836, 2001
Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1
Z Zhang, P Nadeau, W Song, D Donoviel, M Yuan, A Bernstein, ...
Nature cell biology 2 (7), 463-465, 2000
mdmx is a negative regulator of p53 activity in vivo
RA Finch, DB Donoviel, D Potter, M Shi, A Fan, DD Freed, C Wang, ...
Cancer research 62 (11), 3221-3225, 2002
Presenilin-1 and presenilin-2 exhibit distinct yet overlapping γ-secretase activities
MT Lai, E Chen, MC Crouthamel, J DiMuzio-Mower, M Xu, Q Huang, ...
Journal of Biological Chemistry 278 (25), 22475-22481, 2003
Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression
N Sato, F Urano, J Yoon Leem, SH Kim, M Li, D Donoviel, A Bernstein, ...
Nature cell biology 2 (12), 863-870, 2000
Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice
A Shiels, S Bassnett, K Varadaraj, R Mathias, K Al-Ghoul, J Kuszak, ...
Physiological genomics 7 (2), 179-186, 2001
Analysis of muscle creatine kinase gene regulatory elements in skeletal and cardiac muscles of transgenic mice
DB Donoviel, MA Shield, JN Buskin, HS Haugen, CH Clegg, ...
Molecular and cellular biology 16 (4), 1649-1658, 1996
Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice
G Donoho, MA Brenneman, TX Cui, D Donoviel, H Vogel, EH Goodwin, ...
Genes, Chromosomes and Cancer 36 (4), 317-331, 2003
Notch receptor cleavage depends on but is not directly executed by presenilins
Y Taniguchi, H Karlström, J Lundkvist, T Mizutani, A Otaka, M Vestling, ...
Proceedings of the National Academy of Sciences 99 (6), 4014-4019, 2002
Identification and characterization of presenilin-independent Notch signaling
BE Berechid, M Kitzmann, DR Foltz, AH Roach, D Seiffert, LA Thompson, ...
Journal of Biological Chemistry 277 (10), 8154-8165, 2002
High‐throughput screening of mouse knockout lines identifies true lean and obese phenotypes
R Brommage, U Desai, JP Revelli, DB Donoviel, GK Fontenot, ...
Obesity 16 (10), 2362-2367, 2008
The impact of sex and gender on adaptation to space: executive summary
S Mark, GBI Scott, DB Donoviel, LB Leveton, E Mahoney, JB Charles, ...
Journal of women's health 23 (11), 941-947, 2014
Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: induction by basic fibroblast growth factor
DB Donoviel, SL Amacher, KW Judge, P Bornstein
Journal of cellular physiology 145 (1), 16-23, 1990
Structural analysis and expression of the human thrombospondin gene promoter.
DB Donoviel, P Framson, CF Eldridge, M Cooke, S Kobayashi, ...
Journal of Biological Chemistry 263 (35), 18590-18593, 1988
Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene
DB Donoviel, MS Donoviel, E Fan, AK Hadjantonakis, A Bernstein
Mechanisms of development 78 (1-2), 203-207, 1998
Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling
T Takeda, M Asahi, O Yamaguchi, S Hikoso, H Nakayama, Y Kusakari, ...
The FASEB journal 19 (14), 2069-2071, 2005
Functional characterization of novel presenilin-2 variants identified in human breast cancers
MD To, N Gokgoz, TG Doyle, DB Donoviel, JA Knight, PS Hyslop, ...
Oncogene 25 (25), 3557-3564, 2006
A presenilin‐independent aspartyl protease prefers the γ‐42 site cleavage
MT Lai, MC Crouthamel, J DiMuzio, BL Pietrak, DB Donoviel, A Bernstein, ...
Journal of neurochemistry 96 (1), 118-125, 2006
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