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Asen Bagashev
Asen Bagashev
Developing the next generation of immunotherapies
Verified email at carismatx.com - Homepage
Title
Cited by
Cited by
Year
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Cancer discovery 5 (12), 1282-1295, 2015
11922015
CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy
V Pillai, K Muralidharan, W Meng, A Bagashev, DA Oldridge, J Rosenthal, ...
Blood advances 3 (22), 3539-3549, 2019
1622019
Roles and functions of HIV-1 Tat protein in the CNS: an overview
A Bagashev, BE Sawaya
Virology journal 10, 1-20, 2013
1532013
Role of p53 in neurodegenerative diseases
JR Chang, M Ghafouri, R Mukerjee, A Bagashev, T Chabrashvili, ...
Neurodegenerative Diseases 9 (2), 68-80, 2012
1482012
Immune dysregulation in severe influenza
ML Heltzer, SE Coffin, K Maurer, A Bagashev, Z Zhang, JS Orange, ...
Journal of Leucocyte Biology 85 (6), 1036-1043, 2009
1412009
HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs
JR Chang, R Mukerjee, A Bagashev, L Del Valle, T Chabrashvili, ...
Journal of Biological Chemistry 286 (47), 41125-41134, 2011
892011
Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19
M Asnani, KE Hayer, AS Naqvi, S Zheng, SY Yang, D Oldridge, F Ibrahim, ...
Leukemia 34 (4), 1202-1207, 2020
732020
CD19 alterations emerging after CD19-directed immunotherapy cause retention of the misfolded protein in the endoplasmic reticulum
A Bagashev, E Sotillo, CHA Tang, KL Black, J Perazzelli, SH Seeholzer, ...
Molecular and Cellular Biology 38 (21), e00383-18, 2018
592018
Aberrant splicing in B-cell acute lymphoblastic leukemia
KL Black, AS Naqvi, M Asnani, KE Hayer, SY Yang, E Gillespie, ...
Nucleic acids research 46 (21), 11357-11369, 2018
522018
Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders
R Mukerjee, JR Chang, L Del Valle, A Bagashev, MM Gayed, RB Lyde, ...
Journal of Biological Chemistry 286 (40), 34976-34985, 2011
492011
Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL
C Hurtz, GB Wertheim, JP Loftus, D Blumenthal, A Lehman, Y Li, ...
The Journal of clinical investigation 130 (7), 3637-3653, 2020
322020
Leucine-rich repeat (in Flightless I) interacting protein-1 regulates a rapid type I interferon response
A Bagashev, MC Fitzgerald, DF LaRosa, PP Rose, S Cherry, AC Johnson, ...
Journal of Interferon & Cytokine Research 30 (11), 843-852, 2010
312010
Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies
S Zheng, E Gillespie, AS Naqvi, KE Hayer, Z Ang, M Torres-Diz, ...
Blood cancer discovery 3 (2), 103-115, 2022
302022
Myeloid differentiation primary response gene 88 (MyD88) deficiency in a large kindred
DH Conway, J Dara, A Bagashev, KE Sullivan
Journal of allergy and clinical immunology 126 (1), 172-175, 2010
292010
Noncoding RNAs and LRRFIP1 regulate TNF expression
L Shi, L Song, M Fitzgerald, K Maurer, A Bagashev, KE Sullivan
The Journal of Immunology 192 (7), 3057-3067, 2014
282014
HIV-1 Tat protein promotes neuronal dysregulation by inhibiting E2F transcription factor 3 (E2F3)
M Santerre, A Bagashev, L Gorecki, KZ Lysek, Y Wang, J Shrestha, ...
Journal of Biological Chemistry 294 (10), 3618-3633, 2019
272019
Characterization of LRRFIP1
R Arakawa, A Bagashev, L Song, K Maurer, KE Sullivan
Biochemistry and Cell Biology 88 (6), 899-906, 2010
252010
Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein
A Bagashev, S Fan, R Mukerjee, P Paolo Claudio, T Chabrashvili, ...
Cell Cycle 12 (10), 1569-1577, 2013
242013
Convergence of acquired mutations and alternative splicing of CD19 enables resistance to CART-19 immunotherapy. Cancer Discov 5: 1282–1295
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Nat Med 24, 1504-1506, 2015
222015
Combinatorial efficacy of entospletinib and chemotherapy in patient-derived xenograft models of infant acute lymphoblastic leukemia
JP Loftus, A Yahiaoui, PA Brown, LM Niswander, A Bagashev, M Wang, ...
Haematologica 106 (4), 1067, 2021
202021
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