Michael Fossler
Michael Fossler
Trevena, Inc.
Verified email at
Cited by
Cited by
The effects of 4‐aminopyridine in multiple sclerosis patients: Results of a randomized, placebo‐controlled, double‐blind, concentration‐controlled, crossover trial
CT Bever Jr, MD, D Young, PA Anderson, A Krumholz, K Conway, J Leslie, ...
Neurology 44 (6), 1054-1054, 1994
Pharmacometrics: a multidisciplinary field to facilitate critical thinking in drug development and translational research settings
JS Barrett, MJ Fossler, KD Cadieu, MR Gastonguay
The Journal of Clinical Pharmacology 48 (5), 632-649, 2008
A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (μ-GPS) modulator, for the management of moderate to severe …
N Singla, HS Minkowitz, DG Soergel, DA Burt, RA Subach, MY Salamea, ...
Journal of pain research, 2413-2424, 2017
A report from the pediatric formulations task force: perspectives on the state of child-friendly oral dosage forms
A Zajicek, MJ Fossler, JS Barrett, JH Worthington, R Ternik, G Charkoftaki, ...
The AAPS journal 15, 1072-1081, 2013
Dosing in heavy-weight/obese patients with the LMWH, tinzaparin: a pharmacodynamic study
JW Hainer, JS Barrett, CA Assaid, MJ Fossler, DS Cox, T Leathers, ...
Thrombosis and haemostasis 87 (05), 817-823, 2002
Effects of the novel long-acting GLP-1 agonist, albiglutide, on cardiac function, cardiac metabolism, and exercise capacity in patients with chronic heart failure and reduced …
JJ Lepore, E Olson, L Demopoulos, T Haws, Z Fang, AM Barbour, ...
JACC: Heart Failure 4 (7), 559-566, 2016
Population pharmacokinetics of imatinib mesylate and its metabolite in children and young adults
D Menon-Andersen, JT Mondick, B Jayaraman, PA Thompson, ...
Cancer chemotherapy and pharmacology 63, 229-238, 2009
Hospitalized patients with and without hemodialysis have markedly different vancomycin pharmacokinetics: a population pharmacokinetic model-based analysis
V Goti, A Chaturvedula, MJ Fossler, S Mok, JT Jacob
Therapeutic drug monitoring 40 (2), 212-221, 2018
Evaluation of in vitro release rate and in vivo absorption characteristics of four metoprolol tartrate immediate-release tablet formulations
GS Rekhi, ND Eddington, MJ Fossler, P Schwartz, LJ Lesko, ...
Pharmaceutical Development and Technology 2 (1), 11-24, 1997
Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6
D Young, KK Midha, MJ Fossler, EM Hawes, JW Hubbard, G McKay, ...
European journal of clinical pharmacology 44, 433-438, 1993
Identification of formulation and manufacturing variables that influence in vitro dissolution and in vivo bioavailability of propranolol hydrochloride tablets
ND Eddington, M Ashraf, LL Augsburger, JL Leslie, MJ Fossler, LJ Lesko, ...
Pharmaceutical development and technology 3 (4), 535-547, 1998
Benefit and Risk Evaluation of Biased μ-Receptor Agonist Oliceridine versus Morphine
A Dahan, CJ van Dam, M Niesters, M van Velzen, MJ Fossler, ...
Anesthesiology 133 (3), 559-568, 2020
Pharmacokinetics and pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-amino-3 {4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a …
M Qian, SA Bai, B Brogdon, JT Wu, RQ Liu, MB Covington, K Vaddi, ...
Drug metabolism and disposition 35 (10), 1916-1925, 2007
Intravenous and subcutaneous weight-based dosing of the low molecular weight heparin tinzaparin (Innohep) in end-stage renal disease patients undergoing chronic hemodialysis
JW Hainer, DJ Sherrard, SK Swan, JS Barrett, CA Assaid, MJ Fossler, ...
American journal of kidney diseases 40 (3), 531-538, 2002
Modeling the pharmacokinetics and pharmacodynamics of a unique oral hypoglycemic agent using neural networks
SH Haidar, SB Johnson, MJ Fossler, AS Hussain
Pharmaceutical research 19, 87-91, 2002
Oliceridine (TRV130), a novel G protein–biased ligand at the μ‐opioid receptor, demonstrates a predictable relationship between plasma concentrations and pain relief. I …
MJ Fossler, BM Sadler, C Farrell, DA Burt, M Pitsiu, F Skobieranda, ...
The Journal of Clinical Pharmacology 58 (6), 750-761, 2018
Maternofetal pharmacokinetics and fetal lung responses in chronically catheterized sheep receiving constant, low-dose infusions of betamethasone phosphate
MW Kemp, M Saito, H Usuda, TJ Molloy, Y Miura, S Sato, S Watanabe, ...
American journal of obstetrics and gynecology 215 (6), 775. e1-775. e12, 2016
Safety, tolerability, pharmacokinetics and pharmacodynamics of losmapimod following a single intravenous or oral dose in healthy volunteers
AM Barbour, L Sarov‐Blat, G Cai, MJ Fossler, DL Sprecher, J Graggaber, ...
British Journal of Clinical Pharmacology 76 (1), 99-106, 2013
Edible cannabis products: it is time for FDA oversight.
DM Benjamin, MJ Fossler
Journal of clinical pharmacology 56 (9), 2016
Pharmacokinetics and pharmacodynamics of argatroban in combination with a platelet glycoprotein IIB/IIIA receptor antagonist in patients undergoing percutaneous coronary …
DS Cox, NS Kleiman, DA Boyle, J Aluri, LG Parchman, F Holdbrook, ...
The Journal of Clinical Pharmacology 44 (9), 981-990, 2004
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