| From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity JI Castillo-Quan Disease models & mechanisms 5 (3), 293-295, 2012 | 251 | 2012 |
| Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ... Brain 138 (7), 1801-1816, 2015 | 181 | 2015 |
| Lithium promotes longevity through GSK3/NRF2-dependent hormesis JI Castillo-Quan, L Li, KJ Kinghorn, DK Ivanov, LS Tain, C Slack, F Kerr, ... Cell reports 15 (3), 638-650, 2016 | 180 | 2016 |
| A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued … KJ Kinghorn, S Grönke, JI Castillo-Quan, NS Woodling, L Li, E Sirka, ... Journal of Neuroscience 36 (46), 11654-11670, 2016 | 135 | 2016 |
| Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease F Kerr, O Sofola-Adesakin, DK Ivanov, J Gatliff, B Gomez Perez-Nievas, ... PLoS genetics 13 (3), e1006593, 2017 | 126 | 2017 |
| A triple drug combination targeting components of the nutrient-sensing network maximizes longevity JI Castillo-Quan, LS Tain, KJ Kinghorn, L Li, S Grönke, Y Hinze, ... Proceedings of the National Academy of Sciences 116 (42), 20817-20819, 2019 | 76 | 2019 |
| Depresión y diabetes: de la epidemiología a la neurobiología JI Castillo-Quan, DJ Barrera-Buenfil, JM Pérez-Osorio, ... Revista de Neurología 51 (6), 347-359, 2010 | 76 | 2010 |
| Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease O Sofola-Adesakin, JI Castillo-Quan, C Rallis, LS Tain, I Bjedov, I Rogers, ... Frontiers in aging neuroscience 6, 190, 2014 | 69 | 2014 |
| Untangling longevity, dauer, and healthspan in Caenorhabditis elegans insulin/IGF-1-signalling CY Ewald, JI Castillo-Quan, TK Blackwell Gerontology 64 (1), 96-104, 2017 | 63 | 2017 |
| Parkin’control: regulation of PGC-1α through PARIS in Parkinson’s disease JI Castillo-Quan Disease Models & Mechanisms 4 (4), 427-429, 2011 | 59 | 2011 |
| The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease KJ Kinghorn, AM Asghari, JI Castillo-Quan Neural regeneration research 12 (3), 380-384, 2017 | 55 | 2017 |
| Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ... PLoS genetics 16 (11), e1009083, 2020 | 50 | 2020 |
| Genetics and pharmacology of longevity: the road to therapeutics for healthy aging JI Castillo-Quan, KJ Kinghorn, I Bjedov Advances in Genetics 90, 1-101, 2015 | 49 | 2015 |
| Agephagy–adapting autophagy for health during aging ER Stead, JI Castillo-Quan, VEM Miguel, C Lujan, R Ketteler, KJ Kinghorn, ... Frontiers in cell and developmental biology 7, 308, 2019 | 48 | 2019 |
| Metformin: restraining nucleocytoplasmic shuttling to fight cancer and aging JI Castillo-Quan, TK Blackwell Cell 167 (7), 1670-1671, 2016 | 41 | 2016 |
| Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation KJ Kinghorn, JI Castillo-Quan Rare diseases 4 (1), 1801-1816, 2016 | 18 | 2016 |
| Nutritional genomics: an approach to the genome-environment interaction F Xacur-Garcia, JI Castillo-Quan, VM Hernandez-Escalante, ... Rev Med Chil 136, 1460-7, 2008 | 17* | 2008 |
| Insulin-cortisol interaction in depression and other neurological diseases: an alternative hypothesis JI Castillo-Quan, A Herrera-González, JM Pérez-Osorio Psychoneuroendocrinology 32 (7), 854-856, 2007 | 16 | 2007 |
| Cortisol secretion in patients with type 2 diabetes: relationship with chronic complications: response to Chiodini et al. POJM Castillo-Quan, Jorge I Diabetes Care 30 (6), 265-273, 2006 | 13* | 2006 |
| An antisteatosis response regulated by oleic acid through lipid droplet–mediated ERAD enhancement JI Castillo-Quan, MJ Steinbaugh, LP Fernández-Cárdenas, NK Pohl, ... Science Advances 9 (1), eadc8917, 2023 | 12 | 2023 |
Kerri J. KinghornUCLVerified email at ucl.ac.uk
