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Izzy Jayasinghe
Izzy Jayasinghe
Associate Professor, Dept of Molecular Medicine, Faculty of Medicine & Health, UNSW, Sydney
Adresse e-mail validée de unsw.edu.au - Page d'accueil
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Année
Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes
D Baddeley, I Jayasinghe, L Lam, S Rossberger, MB Cannell, C Soeller
Proceedings of the National Academy of Sciences 106 (52), 22275-22280, 2009
3202009
4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues
D Baddeley, D Crossman, S Rossberger, JE Cheyne, JM Montgomery, ...
PloS one 6 (5), e20645, 2011
1622011
Organization of ryanodine receptors, transverse tubules, and sodium-calcium exchanger in rat myocytes
I Jayasinghe, MB Cannell, C Soeller
Biophysical Journal 97 (10), 2664-2673, 2009
1422009
Light-induced dark states of organic fluochromes enable 30 nm resolution imaging in standard media
D Baddeley, I Jayasinghe, C Cremer, MB Cannell, C Soeller
Biophysical journal 96 (2), L22-L24, 2009
1412009
True molecular scale visualization of variable clustering properties of ryanodine receptors
I Jayasinghe, AH Clowsley, R Lin, T Lutz, C Harrison, E Green, ...
Cell Reports 22 (2), 557-567, 2018
1192018
Nanoscale analysis of ryanodine receptor clusters in dyadic couplings of rat cardiac myocytes
Y Hou, I Jayasinghe, DJ Crossman, D Baddeley, C Soeller
Journal of molecular and cellular cardiology 80, 45-55, 2015
1002015
Nanoscale organization of junctophilin-2 and ryanodine receptors within peripheral couplings of rat ventricular cardiomyocytes
ID Jayasinghe, D Baddeley, CHT Kong, XHT Wehrens, MB Cannell, ...
Biophysical journal 102 (5), L19-L21, 2012
742012
Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes
ML Munro, I Jayasinghe, Q Wang, A Quick, W Wang, D Baddeley, ...
Journal of cell science 129 (23), 4388-4398, 2016
712016
Three‐dimensional high‐resolution imaging of cardiac proteins to construct models of intracellular Ca2+ signalling in rat ventricular myocytes
C Soeller, ID Jayasinghe, P Li, AV Holden, MB Cannell
Experimental physiology 94 (5), 496-508, 2009
692009
Comparison of the organization of T‐tubules, sarcoplasmic reticulum and ryanodine receptors in rat and human ventricular myocardium
ID Jayasinghe, DJ Crossman, C Soeller, MB Cannell
Clinical and Experimental Pharmacology and Physiology 39 (5), 469-476, 2012
662012
Three-dimensional reconstruction and analysis of the tubular system of vertebrate skeletal muscle
I Jayasinghe, BS Launikonis
Journal of cell science 126 (17), 4048-4058, 2013
582013
Three-dimensional and chemical mapping of intracellular signaling nanodomains in health and disease with enhanced expansion microscopy
TMD Sheard, ME Hurley, J Colyer, E White, R Norman, E Pervolaraki, ...
ACS nano 13 (2), 2143-2157, 2019
482019
Combining confocal and single molecule localisation microscopy: A correlative approach to multi-scale tissue imaging
DJ Crossman, Y Hou, I Jayasinghe, D Baddeley, C Soeller
Methods 88, 98-108, 2015
442015
Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise
TR Cully, RM Murphy, L Roberts, T Raastad, RG Fassett, JS Coombes, ...
Nature Communications 8 (1), 14266, 2017
402017
Observation of the molecular organization of calcium release sites in fast-and slow-twitch skeletal muscle with nanoscale imaging
ID Jayasinghe, M Munro, D Baddeley, BS Launikonis, C Soeller
Journal of The Royal Society Interface 11 (99), 20140570, 2014
402014
Revealing T-tubules in striated muscle with new optical super-resolution microscopy techniquess
ID Jayasinghe, AH Clowsley, M Munro, Y Hou, DJ Crossman, C Soeller
European journal of translational myology 25 (1), 2015
372015
Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies
KT Miteva, L Pedicini, LA Wilson, I Jayasinghe, RG Slip, K Marszalek, ...
Journal of Cell Biology 218 (7), 2232-2246, 2019
332019
A new twist in cardiac muscle: dislocated and helicoid arrangements of myofibrillar z-disks in mammalian ventricular myocytes
ID Jayasinghe, DJ Crossman, C Soeller, MB Cannell
Journal of molecular and cellular cardiology 48 (5), 964-971, 2010
292010
Algorithmic corrections for localization microscopy with sCMOS cameras-characterisation of a computationally efficient localization approach
R Lin, AH Clowsley, ID Jayasinghe, D Baddeley, C Soeller
Optics express 25 (10), 11701-11716, 2017
282017
Dismantling barriers faced by women in STEM
JM Jebsen, K Nicoll Baines, RA Oliver, I Jayasinghe
Nature Chemistry 14 (11), 1203-1206, 2022
272022
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