Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts H Takayanagi, S Kim, T Koga, H Nishina, M Isshiki, H Yoshida, A Saiura, ... Developmental cell 3 (6), 889-901, 2002 | 2787 | 2002 |
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems H Takayanagi Nature Reviews Immunology 7 (4), 292-304, 2007 | 2056 | 2007 |
Evidence for osteocyte regulation of bone homeostasis through RANKL expression T Nakashima, M Hayashi, T Fukunaga, K Kurata, M Oh-Hora, JQ Feng, ... Nature medicine 17 (10), 1231-1234, 2011 | 1947 | 2011 |
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction K Sato, A Suematsu, K Okamoto, A Yamaguchi, Y Morishita, Y Kadono, ... The Journal of experimental medicine 203 (12), 2673-2682, 2006 | 1828 | 2006 |
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ H Takayanagi, K Ogasawara, S Hida, T Chiba, S Murata, K Sato, ... Nature 408 (6812), 600-605, 2000 | 1624 | 2000 |
T-cell-mediated regulation of osteoclastogenesis by signaling cross-talk between RANKL and IFN-γ H Takayanagi Nature 408, 535-600, 2000 | 1624 | 2000 |
The molecular understanding of osteoclast differentiation M Asagiri, H Takayanagi Bone 40 (2), 251-264, 2007 | 1548 | 2007 |
Estrogen prevents bone loss via estrogen receptor α and induction of Fas ligand in osteoclasts T Nakamura, Y Imai, T Matsumoto, S Sato, K Takeuchi, K Igarashi, ... Cell 130 (5), 811-823, 2007 | 1173 | 2007 |
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis N Komatsu, K Okamoto, S Sawa, T Nakashima, M Oh-Hora, T Kodama, ... Nature medicine 20 (1), 62-68, 2014 | 1168 | 2014 |
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis T Koga, M Inui, K Inoue, S Kim, A Suematsu, E Kobayashi, T Iwata, ... Nature 428 (6984), 758-763, 2004 | 980 | 2004 |
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis M Asagiri, K Sato, T Usami, S Ochi, H Nishina, H Yoshida, I Morita, ... The Journal of experimental medicine 202 (9), 1261-1269, 2005 | 952 | 2005 |
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β H Takayanagi, S Kim, K Matsuo, H Suzuki, T Suzuki, K Sato, T Yokochi, ... Nature 416 (6882), 744-749, 2002 | 824 | 2002 |
Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis H Takayanagi, H Iizuka, T Juji, T Nakagawa, A Yamamoto, T Miyazaki, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2000 | 750 | 2000 |
Osteoprotection by semaphorin 3A M Hayashi, T Nakashima, M Taniguchi, T Kodama, A Kumanogoh, ... Nature 485 (7396), 69-74, 2012 | 657 | 2012 |
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance T Akiyama, Y Shimo, H Yanai, J Qin, D Ohshima, Y Maruyama, Y Asaumi, ... Immunity 29 (3), 423-437, 2008 | 564 | 2008 |
NFAT and Osterix cooperatively regulate bone formation T Koga, Y Matsui, M Asagiri, T Kodama, B de Crombrugghe, K Nakashima, ... Nature medicine 11 (8), 880-885, 2005 | 560 | 2005 |
Osteoimmunology and the effects of the immune system on bone H Takayanagi Nature Reviews. Rheumatology 6 (1), 4, 2010 | 559 | 2010 |
Osteoimmunology and the effects of the immune system on bone H Takayanagi Nature Reviews Rheumatology 5 (12), 667-676, 2009 | 558 | 2009 |
Suppression of bone formation by osteoclastic expression of semaphorin 4D T Negishi-Koga, M Shinohara, N Komatsu, H Bito, T Kodama, RH Friedel, ... Nature medicine 17 (11), 1473-1480, 2011 | 541 | 2011 |
Mechanistic insight into osteoclast differentiation in osteoimmunology H Takayanagi Journal of molecular medicine 83 (3), 170-179, 2005 | 541 | 2005 |