Flemming Steen Jørgensen
Flemming Steen Jørgensen
Professor, Department of Drug Design and Pharmacology, University of Copenhagen
Verified email at sund.ku.dk
Title
Cited by
Cited by
Year
Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities
M Groenning, L Olsen, M van de Weert, JM Flink, S Frokjaer, ...
Journal of structural biology 158 (3), 358-369, 2007
2532007
GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects
P Krogsgaard-Larsen, B Froelund, FS Joergensen, A Schousboe
Journal of medicinal chemistry 37 (16), 2489-2505, 1994
1281994
Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones
C Kunick, K Lauenroth, K Wieking, X Xie, C Schultz, R Gussio, ...
Journal of Medicinal Chemistry 47 (1), 22-36, 2004
1272004
Prediction methods and databases within chemoinformatics: emphasis on drugs and drug candidates
SÓ Jónsdóttir, FS Jørgensen, S Brunak
Bioinformatics 21 (10), 2145-2160, 2005
1252005
A new concept for multidimensional selection of ligand conformations (MultiSelect) and multidimensional scoring (MultiScore) of protein− ligand binding affinities
GE Terp, BN Johansen, IT Christensen, FS Jørgensen
Journal of medicinal chemistry 44 (14), 2333-2343, 2001
1202001
Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter
J Andersen, L Olsen, KB Hansen, O Taboureau, FS Jørgensen, ...
Journal of Biological Chemistry 285 (3), 2051-2063, 2010
1002010
Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques
P Vasanthanathan, O Taboureau, C Oostenbrink, NPE Vermeulen, ...
Drug Metabolism and Disposition 37 (3), 658-664, 2009
982009
hERG classification model based on a combination of support vector machine method and GRIND descriptors
Q Li, FS Jørgensen, T Oprea, S Brunak, O Taboureau
Molecular pharmaceutics 5 (1), 117-127, 2008
972008
Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach
GE Terp, G Cruciani, IT Christensen, FS Jørgensen
Journal of medicinal chemistry 45 (13), 2675-2684, 2002
972002
Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia
AM Buhl, J Jurlander, FS Jørgensen, AM Ottesen, JB Cowland, ...
Blood 107 (7), 2904-2911, 2006
902006
Prediction of pH-dependent aqueous solubility of druglike molecules
NT Hansen, I Kouskoumvekaki, FS Jørgensen, S Brunak, SO Jonsdottir
Journal of chemical information and modeling 46 (6), 2601-2609, 2006
842006
Prediction of cytochrome P450 mediated metabolism
L Olsen, C Oostenbrink, FS Jørgensen
Advanced drug delivery reviews 86, 61-71, 2015
832015
Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands
P Vasanthanathan, J Hritz, O Taboureau, L Olsen, F Steen Jørgensen, ...
Journal of chemical information and modeling 49 (1), 43-52, 2009
792009
Recent advances in GABA agonists, antagonists and uptake inhibitors: structure–activity relationships and therapeutic potential
P KROGSGAARD-LARSEN, H HJEDS, E FALCH, FS JØRGENSEN, ...
Advances in drug research 17, 381-456, 1988
691988
Cyclynes. Part 5. Pericyclynes:" exploded cycloalkanes" with unusual orbital interactions and conformational properties. MM2 and STO-3G calculations, x-ray crystal structures …
KN Houk, LT Scott, NG Rondan, DC Spellmeyer, G Reinhardt, JL Hyun, ...
Journal of the American Chemical Society 107 (23), 6556-6562, 1985
591985
New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design
L Olsen, S Jost, HW Adolph, I Pettersson, L Hemmingsen, FS Jørgensen
Bioorganic & medicinal chemistry 14 (8), 2627-2635, 2006
582006
Solvent diversity in polymorph screening
M Allesø, F Van Den Berg, C Cornett, FS Jørgensen, B Halling-Sørensen, ...
Journal of pharmaceutical sciences 97 (6), 2145-2159, 2008
562008
Towards an understanding of drug resistance in malaria: three-dimensional structure of Plasmodium falciparum dihydrofolate reductase by homology building
T Lemcke, IT Christensen, FS Jørgensen
Bioorganic & medicinal chemistry 7 (6), 1003-1011, 1999
561999
Primary structure and conformational analysis of peptide methionine—tyrosine, a peptide related to neuropeptide Y and peptide YY isolated from lamprey intestine
JM CONLON, B BJØRNHOLM, FS JØRGENSEN, JH YOUSON, ...
European journal of biochemistry 199 (2), 293-298, 1991
561991
Human peptide transporters: therapeutic applications
CU Nielsen, B Brodin, FS Jørgensen, S Frokjaer, B Steffansen
Expert Opinion on Therapeutic Patents 12 (9), 1329-1350, 2002
542002
The system can't perform the operation now. Try again later.
Articles 1–20