Follow
Hugues Chanteux
Hugues Chanteux
UCB BioPharma
Verified email at ucb.com
Title
Cited by
Cited by
Year
Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection …
HHJ Gerets, K Tilmant, B Gerin, H Chanteux, BO Depelchin, S Dhalluin, ...
Cell biology and toxicology 28, 69-87, 2012
7272012
Intracellular pharmacodynamics of antibiotics
S Carryn, H Chanteux, C Seral, MP Mingeot-Leclercq, F Van Bambeke, ...
Infectious Disease Clinics 17 (3), 615-634, 2003
2342003
Comparative stability studies of antipseudomonal β-lactams for potential administration through portable elastomeric pumps (home therapy for cystic fibrosis patients) and motor …
E Viaene, H Chanteux, H Servais, MP Mingeot-Leclercq, PM Tulkens
Antimicrobial agents and chemotherapy 46 (8), 2327-2332, 2002
2192002
LPS induces IL-10 production by human alveolar macrophages via MAPKinases-and Sp1-dependent mechanisms
H Chanteux, AC Guisset, C Pilette, Y Sibille
Respiratory research 8, 1-10, 2007
1872007
Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A (SV 2A) ligand with preclinical evidence of high brain permeability and fast onset of action
JM Nicolas, J Hannestad, D Holden, S Kervyn, N Nabulsi, D Tytgat, ...
Epilepsia 57 (2), 201-209, 2016
1482016
Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats
JP Buts, N De Keyser, S Marandi, D Hermans, EM Sokal, YHE Chae, ...
Gut 45 (1), 89-96, 1999
1091999
Cellular pharmacokinetics and pharmacodynamics of the glycopeptide antibiotic oritavancin (LY333328) in a model of J774 mouse macrophages
F Van Bambeke, S Carryn, C Seral, H Chanteux, D Tyteca, ...
Antimicrobial agents and chemotherapy 48 (8), 2853-2860, 2004
902004
Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages
C Seral, JM Michot, H Chanteux, MP Mingeot-Leclercq, PM Tulkens, ...
Antimicrobial agents and chemotherapy 47 (3), 1047-1051, 2003
852003
Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions
JM Nicolas, F Bouzom, C Hugues, AL Ungell
Biopharmaceutics & drug disposition 38 (3), 209-230, 2017
842017
Stability and compatibility study of cefepime in comparison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory …
N Baririan, H Chanteux, E Viaene, H Servais, PM Tulkens
Journal of Antimicrobial Chemotherapy 51 (3), 651-658, 2003
762003
Brivaracetam and carbamazepine interaction in healthy subjects and in vitro
A Stockis, H Chanteux, M Rosa, P Rolan
Epilepsy Research 113, 19-27, 2015
562015
Effect of rifampin on the disposition of brivaracetam in human subjects: further insights into brivaracetam hydrolysis
A Stockis, S Watanabe, AJ Scheen, D Tytgat, B Gerin, M Rosa, ...
Drug Metabolism and Disposition 44 (6), 792-799, 2016
442016
A review of the drug− drug interactions of the antiepileptic drug brivaracetam
BD Moseley, H Chanteux, JM Nicolas, C Laloyaux, B Gidal, A Stockis
Epilepsy research 163, 106327, 2020
412020
Effect of gemfibrozil on the metabolism of brivaracetam in vitro and in human subjects
JM Nicolas, H Chanteux, M Rosa, S Watanabe, A Stockis
Drug Metabolism and Disposition 40 (8), 1466-1472, 2012
412012
Accumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethylester prodrug, pivampicillin
H Chanteux, F Van Bambeke, MP Mingeot-Leclercq, PM Tulkens
Antimicrobial agents and chemotherapy 49 (4), 1279-1288, 2005
282005
Potential role for human P‐glycoprotein in the transport of lacosamide
C Zhang, H Chanteux, Z Zuo, P Kwan, L Baum
Epilepsia 54 (7), 1154-1160, 2013
272013
Designing out PXR activity on drug discovery projects: a review of structure-based methods, empirical and computational approaches
A Hall, H Chanteux, K Ménochet, M Ledecq, MSED Schulze
Journal of Medicinal Chemistry 64 (10), 6413-6522, 2021
212021
Cell Handling, Membrane-Binding Properties and Membrane-Penetration Modeling Approaches of Pivampicillin and Phthalimidomethylampicillin, Two Basic Esters of Ampicillin, in …
H Chanteux, I Paternotte, MP Mingeot-Leclercq, R Brasseur, E Sonveaux, ...
Pharmaceutical research 20, 624-631, 2003
212003
Assessment of cytochrome P450 (1A2, 2B6, 2C9 and 3A4) induction in cryopreserved human hepatocytes cultured in 48-well plates using the cocktail strategy
B Gerin, S Dell’Aiera, L Richert, S Smith, H Chanteux
Xenobiotica 43 (4), 320-335, 2013
202013
Current practices, gap analysis, and proposed workflows for PBPK modeling of cytochrome P450 induction: an industry perspective
N Hariparsad, D Ramsden, K Taskar, J Badée, K Venkatakrishnan, ...
Clinical Pharmacology & Therapeutics 112 (4), 770-781, 2022
172022
The system can't perform the operation now. Try again later.
Articles 1–20