Sebastian Zeissig
Sebastian Zeissig
University Medical Center Dresden and Center for Regenerative Therapies Dresden
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Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
Microbial exposure during early life has persistent effects on natural killer T cell function
T Olszak, D An, S Zeissig, MP Vera, J Richter, A Franke, JN Glickman, ...
Science 336 (6080), 489-493, 2012
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
A Kaser, AH Lee, A Franke, JN Glickman, S Zeissig, H Tilg, ...
Cell 134 (5), 743-756, 2008
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease
S Zeissig, N Bürgel, D Günzel, J Richter, J Mankertz, U Wahnschaffe, ...
Gut 56 (1), 61-72, 2007
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ...
The Lancet 387 (10014), 156-167, 2016
Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4
Y Junker, S Zeissig, SJ Kim, D Barisani, H Wieser, DA Leffler, V Zevallos, ...
Journal of Experimental Medicine 209 (13), 2395-2408, 2012
International IBD Genetics Consortium (IIBDGC). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells
D An, SF Oh, T Olszak, JF Neves, FY Avci, D Erturk-Hasdemir, X Lu, ...
Cell 156 (1), 123-133, 2014
A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis
S Buch, F Stickel, E Trépo, M Way, A Herrmann, HD Nischalke, M Brosch, ...
Nature genetics 47 (12), 1443-1448, 2015
Epithelial tight junctions in intestinal inflammation
JD Schulzke, S Ploeger, M Amasheh, A Fromm, S Zeissig, H Troeger, ...
Annals of the New York Academy of Sciences 1165 (1), 294-300, 2009
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects
C Schwab, A Gabrysch, P Olbrich, V Patiño, K Warnatz, D Wolff, ...
Journal of Allergy and Clinical Immunology 142 (6), 1932-1946, 2018
Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor α antibody treatment
S Zeissig, C Bojarski, N Buergel, J Mankertz, M Zeitz, M Fromm, ...
Gut 53 (9), 1295-1302, 2004
Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104: H4 induced haemolytic uraemic syndrome: case-control study
J Menne, M Nitschke, R Stingele, M Abu-Tair, J Beneke, J Bramstedt, ...
Bmj 345, 2012
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ...
Nature genetics 47 (2), 172-179, 2015
Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease
S Zeissig, RS Blumberg
Nature immunology 15 (4), 307-310, 2014
Hepatitis B virus–induced lipid alterations contribute to natural killer T cell–dependent protective immunity
S Zeissig, K Murata, L Sweet, J Publicover, Z Hu, A Kaser, E Bosse, ...
Nature medicine 18 (7), 1060-1068, 2012
Disrupted barrier function through epithelial cell apoptosis
JD SCHULZKE, C Bojarski, S Zeissig, F Heller, AH Gitter, M Fromm
Annals of the New York Academy of Sciences 1072 (1), 288-299, 2006
Protective mucosal immunity mediated by epithelial CD1d and IL-10
T Olszak, JF Neves, CM Dowds, K Baker, J Glickman, NO Davidson, ...
Nature 509 (7501), 497-502, 2014
HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
GA Heap, MN Weedon, CM Bewshea, A Singh, M Chen, JB Satchwell, ...
Nature genetics 46 (10), 1131-1134, 2014
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
S Zeissig, E Rosati, CM Dowds, K Aden, J Bethge, B Schulte, WH Pan, ...
Gut 68 (1), 25-39, 2019
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