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James Kath
James Kath
Senior Scientist, Chemical Biology, AbbVie, Inc.
Verified email at abbvie.com
Title
Cited by
Cited by
Year
Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis
JE Kath, S Jergic, JMH Heltzel, DT Jacob, NE Dixon, MD Sutton, ...
Proceedings of the National Academy of Sciences 111 (21), 7647-7652, 2014
932014
A cell‐free platform for rapid synthesis and testing of active oligosaccharyltransferases
JA Schoborg, JM Hershewe, JC Stark, W Kightlinger, JE Kath, ...
Biotechnology and bioengineering, 2017
912017
Exchange between Escherichia coli polymerases II and III on a processivity clamp
JE Kath, S Chang, MK Scotland, JH Wilbertz, S Jergic, NE Dixon, ...
Nucleic acids research 44 (4), 1681-1690, 2016
382016
Single-molecule imaging reveals multiple pathways for the recruitment of translesion polymerases after DNA damage
ES Thrall, JE Kath, S Chang, JJ Loparo
Nature communications 8 (1), 2170, 2017
342017
A Genetic Selection for dinB Mutants Reveals an Interaction between DNA Polymerase IV and the Replicative Polymerase That Is Required for Translesion Synthesis
MK Scotland, JMH Heltzel, JE Kath, JS Choi, AJ Berdis, JJ Loparo, ...
PLoS genetics 11 (9), e1005507, 2015
332015
Remote control of DNA-acting enzymes by varying the Brownian dynamics of a distant DNA end
H Bai, JE Kath, FM Zörgiebel, M Sun, P Ghosh, GF Hatfull, NDF Grindley, ...
Proceedings of the National Academy of Sciences 109 (41), 16546-16551, 2012
292012
A gatekeeping function of the replicative polymerase controls pathway choice in the resolution of lesion-stalled replisomes
S Chang, K Naiman, ES Thrall, JE Kath, S Jergic, NE Dixon, RP Fuchs, ...
Proceedings of the National Academy of Sciences 116 (51), 25591-25601, 2019
172019
Characterizing and controlling nanoscale self-assembly of suckerin-12
JM Hershewe, WD Wiseman, JE Kath, CC Buck, MK Gupta, PB Dennis, ...
ACS synthetic biology 9 (12), 3388-3399, 2020
122020
Target engagement approaches for pharmacological evaluation in animal models
JE Kath, A Baranczak
Chemical Communications 55 (63), 9241-9250, 2019
52019
Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications
S Patel, M Karlsson, JT Klahn, F Gambino, H Costa, KA McGuire, ...
SLAS Discovery, 2023
2023
DNA Polymerase Exchange and Lesion Bypass in Escherichia Coli
JE Kath
2015
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