Trapping biosynthetic acyl-enzyme intermediates with encoded 2, 3-diaminopropionic acid N Huguenin-Dezot, DA Alonzo, GW Heberlig, M Mahesh, DP Nguyen, ... Nature 565 (7737), 112-117, 2019 | 96 | 2019 |
Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1 BR Lundgren, W Thornton, MH Dornan, LR Villegas-Peñaranda, ... Journal of bacteriology 195 (9), 2087-2100, 2013 | 60 | 2013 |
First-in-class small molecule potentiators of cancer virotherapy MH Dornan, R Krishnan, AM Macklin, M Selman, N El Sayes, HH Son, ... Scientific reports 6 (1), 26786, 2016 | 40 | 2016 |
Impact of Detergents on Membrane Protein Complex Isolation YC Lee, JA Bååth, RM Bastle, S Bhattacharjee, MJ Cantoria, ... Journal of proteome research 17 (1), 348-358, 2018 | 34 | 2018 |
Simplified and robust one‐step radiosynthesis of [18F]DCFPyL via direct radiofluorination and cartridge‐based purification MH Dornan, JM Simard, A Leblond, D Juneau, G Delouya, F Saad, ... Journal of Labelled Compounds and Radiopharmaceuticals 61 (10), 757-763, 2018 | 16 | 2018 |
Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria P Labana, MH Dornan, M Lafrenière, TL Czarny, ED Brown, JP Pezacki, ... Cell Chemical Biology 28 (12), 1703-1715. e11, 2021 | 10 | 2021 |
Hexanes/acetonitrile: a binary solvent system for the efficient monosilylation of symmetric primary and secondary diols BI Wilke, MH Dornan, J Yeung, CN Boddy, A Pinto Tetrahedron letters 55 (16), 2600-2602, 2014 | 10 | 2014 |
Pre-clinical characterization of the novel FAP targeting ligand PNT6555 for the imaging and therapy of cancer R Hallett, S Poplawski, K Novakowski, M Dornan, SH Ahn, S Pan, W Wu, ... Journal of Nuclear Medicine 63 (supplement 2), 4028-4028, 2022 | 6 | 2022 |
A high molar activity 18F-labeled TAK-875 derivative for PET imaging of pancreatic β-cells MH Dornan, D Petrenyov, JM Simard, A Aliaga, G Xiong, J Ghislain, ... EJNMMI Radiopharmacy and Chemistry 3, 1-15, 2018 | 4 | 2018 |
Armeniaspirol analogues with more potent Gram-positive antibiotic activity show enhanced inhibition of the ATP-dependent proteases ClpXP and ClpYQ MG Darnowski, TD Lanosky, P Labana, JT Brazeau-Henrie, ND Calvert, ... RSC Medicinal Chemistry 13 (4), 436-444, 2022 | 3 | 2022 |
Synthesis of a 11C-Isotopologue of the B-Raf-Selective Inhibitor Encorafenib Using In-Loop [11C]CO2 Fixation MH Dornan, D Petrenyov, JM Simard, M Boudjemeline, R Mititelu, ... ACS omega 5 (33), 20960-20966, 2020 | 3 | 2020 |
Compositions and methods for viral sensitization JS Diallo, CN Boddy, M Dornan, R Krishnan, R Arulanandam, F Le Boeuf, ... US Patent 10,654,839, 2020 | 3 | 2020 |
Radiosynthesis of the 11C‐methyl derivative of LBQ657 for PET investigation of the neprilysin inhibitor sacubitril VR Teyssier, JM Simard, MH Dornan, F Tournoux, JN DaSilva Journal of Labelled Compounds and Radiopharmaceuticals 63 (2), 65-71, 2020 | 2 | 2020 |
Preclinical Development of PNT6555, a Boronic Acid–Based, Fibroblast Activation Protein-α (FAP)–Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors SE Poplawski, RM Hallett, MH Dornan, KE Novakowski, S Pan, ... Journal of Nuclear Medicine 65 (1), 100-108, 2024 | 1 | 2024 |
Development and characterization of a next-generation Ac-225-PSMA radioligand A Vito, M Dornan, T Beale, A Felten, M Ernste, Q Nguyen, S Ahn, ... EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 49 (SUPPL 1 …, 2022 | 1 | 2022 |
Compositions and methods for enhancing oncolytic virus efficacy JS Diallo, CN Boddy, M Dornan, R Krishnan, F Le Boeuf, JC Bell, ... US Patent App. 15/542,480, 2018 | 1 | 2018 |
Compositions and methods for viral sensitization JS Diallo, CN BODDY, M DORNAN, R KRISHNAN, R ARULANANDAM, ... | 1 | 2016 |
Method development for centralized clinical production of 177Lu-PNT2002 M Dornan, L Southcott, SH Ahn, A Belanger, V Hergott, J McCann Nuclear Medicine and Biology 126, 108540, 2023 | | 2023 |
Preclinical application of novel isotopes and combination therapy with the FAP targeting ligand PNT6555 K Novakowski, SH Ahn, M Dornan, A Belanger, S Poplawski, ... Journal of Nuclear Medicine 64 (supplement 1), P180-P180, 2023 | | 2023 |
Compositions and methods for viral sensitization JS Diallo, CN Boddy, M Dornan, R Krishnan, R Arulanandam, F Le Boeuf, ... US Patent App. 17/710,386, 2022 | | 2022 |