Follow
Kevin Frankowski
Kevin Frankowski
Assistant Professor of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy
Verified email at unc.edu - Homepage
Title
Cited by
Cited by
Year
Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction
KJ Frankowski, JE Golden, Y Zeng, Y Lei, J Aubé
Journal of the American Chemical Society 130 (18), 6018-6024, 2008
1552008
Development of functionally selective, small molecule agonists at kappa opioid receptors
L Zhou, KM Lovell, KJ Frankowski, SR Slauson, AM Phillips, JM Streicher, ...
Journal of Biological Chemistry 288 (51), 36703-36716, 2013
1542013
Structure–activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase
TF Chou, K Li, KJ Frankowski, FJ Schoenen, RJ Deshaies
ChemMedChem 8 (2), 297-312, 2013
1472013
Grubbs' catalyst in paraffin: An air-stable preparation for alkene metathesis
DF Taber, KJ Frankowski
The Journal of organic chemistry 68 (15), 6047-6048, 2003
1062003
Practical electrochemical anodic oxidation of polycyclic lactams for late stage functionalization
KJ Frankowski, R Liu, GL Milligan, KD Moeller, J Aubé
Angewandte Chemie International Edition 54 (36), 10555-10558, 2015
872015
Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline
K Li, KJ Frankowski, CA Belon, B Neuenswander, J Ndjomou, AM Hanson, ...
Journal of medicinal chemistry 55 (7), 3319-3330, 2012
732012
Chemotype-selective modes of action of κ-opioid receptor agonists
E Vardy, PD Mosier, KJ Frankowski, H Wu, V Katritch, RB Westkaemper, ...
Journal of Biological Chemistry 288 (48), 34470-34483, 2013
682013
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis
KJ Frankowski, C Wang, S Patnaik, FJ Schoenen, N Southall, D Li, ...
Science translational medicine 10 (441), eaap8307, 2018
632018
structure–activity relationship studies of functionally selective kappa opioid receptor agonists that modulate ERK 1/2 phosphorylation while preserving G protein over …
KM Lovell, KJ Frankowski, EL Stahl, SR Slauson, E Yoo, TE Prisinzano, ...
ACS chemical neuroscience 6 (8), 1411-1419, 2015
612015
Benzothiazole and pyrrolone flavivirus inhibitors targeting the viral helicase
NL Sweeney, AM Hanson, S Mukherjee, J Ndjomou, BJ Geiss, JJ Steel, ...
ACS infectious diseases 1 (3), 140-148, 2015
582015
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays
S Mukherjee, AM Hanson, WR Shadrick, J Ndjomou, NL Sweeney, ...
Nucleic Acids Research 40 (17), 8607-8621, 2012
562012
A multicenter study investigating SARS-CoV-2 in tertiary-care hospital wastewater. viral burden correlates with increasing hospitalized cases as well as hospital-associated …
N Acosta, MA Bautista, J Hollman, J McCalder, AB Beaudet, L Man, ...
Water Research 201, 117369, 2021
552021
Discovery of small molecule kappa opioid receptor agonist and antagonist chemotypes through a HTS and hit refinement strategy
KJ Frankowski, MP Hedrick, P Gosalia, K Li, S Shi, D Whipple, P Ghosh, ...
ACS chemical neuroscience 3 (3), 221-236, 2012
532012
Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus
J Morgenweck, KJ Frankowski, TE Prisinzano, J Aubé, LM Bohn
Neuropharmacology 99, 600-609, 2015
472015
Grubbs's cross metathesis of eugenol with cis-2-butene-1, 4-diol to make a natural product. An organometallic experiment for the undergraduate lab
DF Taber, KJ Frankowski
Journal of chemical education 83 (2), 283, 2006
472006
Efficient synthesis of γ-lactams by a tandem reductive amination/lactamization sequence
J Nöth, KJ Frankowski, B Neuenswander, J Aubé, O Reiser
Journal of combinatorial chemistry 10 (3), 456-459, 2008
442008
Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands
KJ Frankowski, V Setola, JM Evans, B Neuenswander, BL Roth, J Aubé
Proceedings of the National Academy of Sciences 108 (17), 6727-6732, 2011
422011
Synthesis of (+)-sulcatine G
DF Taber, KJ Frankowski
The Journal of Organic Chemistry 70 (16), 6417-6421, 2005
422005
Longitudinal SARS-CoV-2 RNA wastewater monitoring across a range of scales correlates with total and regional COVID-19 burden in a well-defined urban population
N Acosta, MA Bautista, BJ Waddell, J McCalder, AB Beaudet, L Man, ...
Water Research 220, 118611, 2022
382022
Identification of positive allosteric modulators of the D1 dopamine receptor that act at diverse binding sites
KD Luderman, JL Conroy, RB Free, N Southall, M Ferrer, M Sanchez-Soto, ...
Molecular Pharmacology 94 (4), 1197-1209, 2018
382018
The system can't perform the operation now. Try again later.
Articles 1–20